Handling carbon tetrafluoride (CF4) requires careful safety measures due to its physical properties and potential health effects. While CF4 is non-toxic and non-flammable, it is a dense gas that can displace oxygen in confined spaces, creating an oxygen-deficient environment that can cause asphyxiation.

Proper ventilation is essential when working with CF4. If a leak occurs, the area should be evacuated and the gas allowed to vent to the atmosphere. If this is not possible, respiratory protection may be required.

CF4 should be stored in a cool, well-ventilated area away from ignition sources. Although CF4 will not burn, it may cause other materials to burn more vigorously. Therefore, it's best to store